Ephedra may be used in hyperthyroidism, hypertension and cardiac patients only with the greatest care, and only for a short time. Ephedra or ephedrine, in combination with other sympathomimetic substances such as caffeine, yohimbine and the like, can increase the effect. Uncontrolled use of ephedra, for weight loss and performance enhancement, can be dangerous. In top athletes it is contraindicated, since ephedrineuse is considered doping.

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